Is 1500 mg of berberine a day too much?

1,500 milligrams of berberine has no official upper limit. It can cause nausea, bloating, constipation or diarrhoea.

Checked 28 September 2026 · Sources: NCCIH (US National Institutes of Health) · Adults onlyNo official upper limit

General information, not medical advice. Check with a doctor or pharmacist before taking a supplement, especially if you are pregnant or breastfeeding, take any medicine, or are under 18.

The figures

Amount checked1,500 mg
AnswerNo official upper limit

Cautions and interactions

Quick answers

Is 1500 mg of berberine a day too much?
1,500 milligrams of berberine has no official upper limit. It can cause nausea, bloating, constipation or diarrhoea.
Is berberine safe?
It can cause nausea, bloating, constipation or diarrhoea. It interacts with cyclosporine and may be unsafe in pregnancy or breastfeeding.

Sources

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